Genomic engineering is direct manipulation of an organism’s genome (DNA) to alter its characteristics. It enables scientists to
• Study gene functions
• Model human diseases
• Correct mutations in diseased cells and tissues
• Control infectious diseases • Increase crop production…
• Most multicellular organisms’ genomes are vast. For example, each human cell contains ~ 6 billion base- pairs of DNA!
• It’s extremely time-consuming and expensive to generate precise and targeted modifications in complex genomes using conventional tools