Modeling the number of individuals in different states is a principal tool in the event of an epidemic. The natural transition of individuals between possible states often includes deliberate interference such as isolation or vaccination. Thus, the mathematical model may need to be re-calibrated due to various factors. The model considered in this paper is the SIRD epidemic model. An additional parameter is the moment of changing the description of the phenomenon when the parameters of the model change and the change is not pre-specified. Detecting and estimating the moment of change in real time is the subject of statistical research. A sequential (online) approach was applied using the Bayesian shift point detection algorithm and trimmed exact linear time. We show how methods of analysis behave in different instances. These methods are verified on simulated data and applied to pandemic data of a selected European country. The simulation is performed with a social network graph to obtain a practical representation ability. The epidemiological data used come from the territory of Poland and concern the COVID-19 epidemic in Poland. The results show satisfactory detection of the moments where the applied model needs to be verified and re-calibrated. These show the effectiveness of the proposed combination of methods.