Browse the Biology Collections
« Previous | 6 - 6 of 6 | Next »
Genetic disruption of the mouse oxytocin system results in sex-specific differences in social memory and neuronal activation
Oxytocin (Oxt) is a neuropeptide that regulates social behavior and is important for the proper functioning of social memory. In rodents, social memory is frequently tested using a social discrimination test. It was hypothesized that male and female mice with disruptions in either their Oxt (—/—) or their Oxt receptor (Oxtr —/—), genes would have differing social memory and unique patterns of neuronal activation. To date, behavioral testing and immunostaining for c-Fos (a protein used to measure neuronal activation) have been completed, but data not yet processed. No matter the findings, this work will lay the foundation for future work on the role of the Oxt system in forms of memory.