1. Open Access Kent State
  2. A Brief Review of the Structure, Cytotoxicity, Synthesis, and Biodegradation of Microcystins
Author(s)
Abstract

Harmful cyanobacterial blooms pose an environmental health hazard due to the release of water-soluble cyanotoxins. One of the most prevalent cyanotoxins in nature is microcystins (MCs), a class of cyclic heptapeptide hepatotoxins, and they are produced by several common cyanobacteria in aquatic environments. Once released from cyanobacterial cells, MCs are subjected to physical chemical and biological transformations in natural environments. MCs can also be taken up and accumulated in aquatic organisms and their grazers/predators and induce toxic effects in several organisms, including humans. This brief review aimed to summarize our current understanding on the chemical structure, exposure pathway, cytotoxicity, biosynthesis, and environmental transformation of microcystins.
Format
Article
Identifier(s)
10.3390/w13162147
Publication Date
2021-08-05
Publication Title
Water
Publisher
MDPI
Volume
13
Issue
16
First Page
2147
Keywords
Subject
Rights
http://rightsstatements.org/vocab/InC/1.0/
https://www.mdpi.com/openaccess
License
Creative Commons Attribution 4.0
Community
Department of Biological Sciences
Permalink https://oaks.kent.edu/article/brief-review-structure-cytotoxicity-synthesis-and-biodegradation-microcystins
Krishnan, A., & Mou, X. (2021). A Brief Review of the Structure, Cytotoxicity, Synthesis, and Biodegradation of Microcystins (1–). Water. https://doi.org/10.3390/w13162147
Krishnan, Anjali, and Xiaozhen Mou. 2021. “A Brief Review of the Structure, Cytotoxicity, Synthesis, and Biodegradation of Microcystins”. Water. https://doi.org/10.3390/w13162147.
Krishnan, Anjali, and Xiaozhen Mou. A Brief Review of the Structure, Cytotoxicity, Synthesis, and Biodegradation of Microcystins. Water, 5 Aug. 2021, https://doi.org/10.3390/w13162147.