1. Open Access Kent State
  2. Cooperative chiral order in the B-Z transition in random sequences of DNA
Author(s)
Abstract

We present a theory for cooperative chiral order in the transition between right-handed B-DNA and left-handed Z-DNA. This theory, based on the random-field Ising model, predicts the characteristic length scale of Z-DNA segments. This length scale depends on whether the DNA is a homopolymer or a random sequence: it is approximately 4000 nucleotides in a homopolymer but only approximately 25 nucleotides in a random sequence. These theoretical results are consistent with experiments on DNA homopolymers and random sequences.
Format
Article
Identifier(s)
10.1016/S0006-3495(97)78129-3
Scopus EID: 2-s2.0-0030797040
Publication Date
1997-08
Publication Title
Biophysical Journal
Publisher
Cell Press
Volume
73
Issue
2
First Page
966
Last Page
971
Subject
Rights
http://rightsstatements.org/vocab/InC/1.0/
Community
Advanced Materials and Liquid Crystal Institute
Department of Physics
Permalink https://oaks.kent.edu/article/cooperative-chiral-order-b-z-transition-random-sequences-dna
Selinger, J., & Schnur, J. (1997). Cooperative chiral order in the B-Z transition in random sequences of DNA (1–). Biophysical Journal. https://doi.org/10.1016/S0006-3495(97)78129-3
Selinger, Jonathan, and Joel Schnur. 1997. “Cooperative Chiral Order in the B-Z Transition in Random Sequences of DNA”. Biophysical Journal. https://doi.org/10.1016/S0006-3495(97)78129-3.
Selinger, Jonathan, and Joel Schnur. Cooperative Chiral Order in the B-Z Transition in Random Sequences of DNA. Biophysical Journal, Aug. 1997, https://doi.org/10.1016/S0006-3495(97)78129-3.