In prior research, Jamali et al. demonstrated the efficacy of a 20-mm aperture liquid crystal (LC) tunable lens for both accommodation-convergence mismatch correction and presbyopia correction. This lens employed a concentric ring electrode-based LC design with a segmented phase profile, enabling a larger aperture size without affecting switching speed. However, for near-eye application, a high optical quality LC lens with larger than 20-mm aperture size is a requirement to allow large field of view. Therefore, we report here a 50-mm aperture LC lens with incorporated solutions to minimize haze that results due to the large aperture size. Due to its large aperture size, fast switching speed, compact size, and low voltage operation, the reported 50 mm LC lens is a practical option for near-to-eye applications and other tunable lens applications. The objective of this paper is to provide a comprehensive detail on the design, modeling, fabrication, and characterization of the optical quality of the developed 50 mm LC lens. Quantitative assessments of the lens’s optical quality are presented across the entire aperture, with a particular focus on near-eye applications.