COVID-19 and emerging viral infections: The case for interferon lambda

Department of Biological Sciences
  1. Open Access Kent State
  2. Kent State University COVID-19 research and funded grants
  3. COVID-19 and emerging viral infections: The case for interferon lambda
Author(s)
Abstract

With the first reports on coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the scientific community working in the field of type III IFNs (IFN-λ) realized that this class of IFNs could play an important role in this and other emerging viral infections. In this Viewpoint, we present our opinion on the benefits and potential limitations of using IFN-λ to prevent, limit, and treat these dangerous viral infections.
Format
Article
Identifier(s)
10.1084/jem.20200653
Publication Date
2020-04-14
Publication Title
The Journal of experimental medicine
Publisher
Rockefeller University Press
Volume
217
Issue
5
Keywords
License
Creative Commons Attribution-Noncommercial-Share Alike 4.0
Community
Department of Biological Sciences
Permalink https://oaks.kent.edu/covid19ksu/covid-19-and-emerging-viral-infections-case-interferon-lambda
Piontkivska, H., Prokunina-Olsson, L., Alphonse, N., Dickenson, R., Durbin, J., Glenn, J., Hartmann, R., Kotenko, S., Lazear, H., O’Brien, T., Odendall, C., Onabajo, O., Santer, D., Reich, N., Wack, A., & Zanoni, I. (2020). COVID-19 and emerging viral infections: The case for interferon lambda. The Journal of experimental medicine. https://doi.org/https://doi.org/10.1084/jem.20200653
Piontkivska, Helen, Ludmila Prokunina-Olsson, Noémie Alphonse, Ruth Dickenson, Joan Durbin, Jeffrey Glenn, Rune Hartmann, Sergei Kotenko, Helen Lazear, Thomas O’Brien, Charlotte Odendall, Olusegun Onabajo, Deanna Santer, Nancy Reich, Andreas Wack, and Ivan Zanoni. 2020. “COVID-19 and Emerging Viral Infections: The Case for Interferon Lambda”. The Journal of experimental medicine. https://doi.org/https://doi.org/10.1084/jem.20200653.
Piontkivska, H., L. Prokunina-Olsson, N. Alphonse, R. Dickenson, J. Durbin, J. Glenn, R. Hartmann, S. Kotenko, H. Lazear, T. O’Brien, C. Odendall, O. Onabajo, D. Santer, N. Reich, A. Wack, and I. Zanoni. COVID-19 and Emerging Viral Infections: The Case for Interferon Lambda. The Journal of experimental medicine, 14 Apr. 2020, doi:https://doi.org/10.1084/jem.20200653.