Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system caused by inflammation and progressive demyelination, causing biological and psychological issues. Up to 65% of MS patients have cognitive dysfunction that significantly affects their ability to function, and this negatively impacts employment and sociability than cognitively intact MS patients suffering from physical ailments. (Wilken et al., 2003). This disengagement from social activities and employment could be because MS is associated with high rates of depression. The lifetime prevalence for depression in MS is 50% and the annual prevalence of 20% which are very high. (Siegert and Abernethy, 2005). We want to determine how damage to executive planning by MS impacts the level of depression over time. We examined a sample of recently diagnosed patients with MS over the course of 18 months. We tested their cognition with the Tower Puzzle from the Automated Neuropsychological Assessment Metrics which measures executive planning. This test was administered at 1 and 13 months. We used the Center for Epidemiologic Studies Depression (CES-D) Scale to test the level of depression symptoms. We will use a within-subject t-test to determine if there is a sample-wide difference in performance on the Tower Puzzle; then, we will use a correlation to test if change in the tower score is associated with depression symptoms that were measured with the CES-D scale. This research will help patients that need more support because we will understand how the damage MS does to executive planning may impact future mental illness.