The purpose of this project was to enhance a large format course with an enrollment of approximately 130 students. The course was redeveloped and students were given flexibility and choice. Each lecture was accompanied by a clicker activity. Alternatively, there was a BbLearn quiz on the same topic from the textbook, available for 24 hours prior to the end of that day’s class. On a day-to-day basis, students could choose to learn in the auditorium or elsewhere online. Student evaluations show positive reception to the “hybrid by choice” arrangement. Large enrollment courses can effectively retain the lecture format, yet become more engaging by integrating creative solutions. One caveat, “hybrid by choice” needs to be coupled by a dynamic lecture. Without the additional resources of embedded videos and museum artifacts, there would be little competition between a “straight” lecture and the online quiz.