Taking into account several existing structures and considering progressive collapse for blast conditions, designing it both effectively and economically is a top priority for a lot of Stakeholders, Engineers & Architects. The argument for Steel vs Concrete still raises a question, which holds better? And which offers more load carrying capacity, sustainability and longevity particularly against loads such as seismic and wind loads? In most cases, one can argue that both can be used to deliver an effective structural carrying capacity. Steel and concrete buildings have a rather symbiotic relationship with the viewpoint that Pre-engineered Steel buildings generally rely on the strength of a concrete slab or a stem wall foundation, resting on it to produce additional support and the capacity for durability. In its entirety, it all comes down to the kind of design, what better suits our design as architects, meaning both can serve/work together efficiently. This research aims to expand on the comparison between steel versus concrete, and the possibility of optimal integration of the structural elements also looking into more specifically at reinforced concrete buildings versus pre-engineered steel building systems not limited to the versatility, availability, and durability of both. Thereby helping people understand the two in comparison and the possibilities for optimization.